Qualifications & Selected Publications...
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Harry Ridgway has been engaged in the research and development of water purification membranes and membrane processes for more than two decades. From 1981 until 2002, Dr. Ridgway served as the Research Director for the Orange County Water District (OCWD) in Fountain Valley, California, home of Water Factory 21, the world's first large-scale application of reverse osmosis (RO) membrane technology for water reuse. While at OCWD, Dr. Ridgway pioneered the development of novel methods for carrying out detailed studies on the mechanism and dynamics of bacterial adhesion and biofilm formation on RO membrane materials, a phenomenon known as membrane biofouling. While membrane biofouling still remains a serious problem in many membrane applications, the results of his early work helped shape the current generation of commercial low-fouling polyamide RO membrane materials. More recently, Dr. Ridgway has developed computer programs that enable molecular modeling of novel crosslinked polymer membrane materials. The computer programs facilitate exploration of many theoretical aspects of water and solute transport through RO membrane materials. They also provide fresh insight into the mechanisms of foulant adsorption to membrane surfaces. Dr. Ridgway received a Bachelor of Science degree in Microbiology (and a minor in Chemistry) in 1971 from San Diego State University and a PhD in Marine Microbiology from Scripps Institute of Oceanography in 1976.  His doctoral research focused on the ultrastructural and biochemical basis of gliding motility in the filamentous marine bacterium Flexibacter polymorphus. From 1976 to 1978, Dr. Ridgway was a postdoctoral research fellow at the University of California, San Diego where he performed fundamental genetic and biochemical studies on the mechanism of motility and chemotaxis in the bacterium Escherichia coli. From 1978 to 1981, Dr. Ridgway joined the University of California, Irvine where he conducted additional postdoctoral studies on the microbiology of drinking water distrubtion systems.  It was during that period that he became interested in the interaction of bacteria with RO membrane materials. Dr. Ridgway currently holds a Consulting Professorship with Stanford University in the Civil and Environmental Engineering Department and in 2002 he was awarded the Athalie Richardson Irvine Clarke Prize for his pioneering contributions in the area of membrane biofouling.  AquaMem Scientific Consultants maintains active national and international collaborations with several universities and government entities.
Selected Reports, Publications & Presentations...
Steinle-Darling, E., Zedda, M., Plumlee, M.H., Ridgway, H.F. and M. Reinhard.  2007. Evaluating the impacts of membrane type, coating, fouling, chemical properties and water chemistry on reverse osmosis rejection of seven nitrosoalklyamines, including NDMA.  Journal of Membrane Science, in press.
Rodriguez, G., Buonora, S., Knoell, T., Phipps, D. and H. Ridgway.  2004.  Rejection of pharmaceuticals by reverse osmosis (RO) membranes:  quantitative structure activity relationship (QSAR) analysis.  Final project report submitted to the National Water Research Institute, NWRI Project No. 01-EC-002.
Ridgway, H.F., Ishida, K., and D. Phipps. Membrane Improvement Using Molecular Modeling:  Strategies for Modeling Performance and Fouling, Water Reuse and Desalination Conference, 25-27 Singapore, International Desalination Association (2003).
Riley, R. L.,  Lin, S. W., Murphy, A.,  Wiater-Protas, I. and H. F. Ridgway. 2002. Development of a New Chlorine and Biofouling Resistant Polyamide Membrane. Final project report submitted to the US Army, Report No. A273214.
Project Development Group, Orange County Water District, Fountain Valley, California.  2002.  Investigation of chlorine tolerant thin-film composite reverse osmosis membranes. Project report submitted to the California Energy Commission, Project Task 2.4 B 1.
R. L. Riley; S. W. Lin; A. Murphy; H. F. Ridgway; K. P. Ishida. 2001. Development of Improved Membranes for ROWPU Spiral_Wound Elements. Final project report 13 Nov 1998-1 Mar 2001, Phase 2, U.S. Army Report Number A650093.
Knoell, T., J. Safarik, T. Cormack, R. Riley, S.W. Lin and H. Ridgway.  2000.  Biofouling potentials of  microporous polysulfone membranes containing a sulfonated polyethersulfone -  polyethersulfone block copolymer:  correlation of membrane surface properties with  bacterial attachment.  Journal of Membrane Science, 157, 117-138.
Campbell, P., Srinivasan, R., Knoell, T., Phipps, D., Ishida, K., Safarik, J., Cormack, T. and H. F. Ridgway. 1999. Quantitative structure activity realtionship (QSAR) analysis of surfactants influencing attachment of a Mycobacterium species to cellulose acetate and polyamide reverse osmosis membranes.  Biotechnol. Bioengineering 64, 527-544.
Ridgway, H. F., K. Ishida, G. Rodriguez, J. Safarik, T. Knoell and R. Bold.  1999.  Biofouling of Membranes:  Membrane Preparation, Characterization, and Analysis of Bacterial Adhesion, pp. 463-494. In Doyle, R. (Ed.), Methods in Enzymology:  Biofilms, Academic Press, San Diego, CA.
Mirpuri R.G., Jones W.L., McFeters G.A., Ridgway H.F. 1997. Physiological stress in batch cultures of Pseudomonas putida 54G during toluene degradation. J. Ind. Microbiol. &  Biotechnol. 6, 406-13.
Phipps, D., G. Rodriguez and H.F. Ridgway.  1999.  Deconvolution Fluorescence Microscopy for Observation and Analysis of Membrane Biofilm Architecture, pp. 178-194.  In Doyle, R. (Ed.), Methods in Enzymology:  Biofilms, Academic Press, San Diego, CA.
Foght, J.M., Westlake, W.S., Johnson, W.M. and H.F. Ridgway.  1996.  Environmental gasoline-utilizing isolates and clinical isolates of Pseudomonas aeruginosa are indistinguishable by chemotaxonomic and molecular techniques.  Microbiology 142, 2333-2340.
Ridgway, H. F.,  Molecular Modeling of Organics Adsorption to Synthetic Polymer Membranes,  Proc.  International Membrane Science and Technology Conference, 12-14 November 1996, Sydney,  Australia (1996).
Ridgway, H. F. and H. C. Flemming.  1996.  Membrane Biofouling, pp 6.1-6.62, In: Water Treatment: Membrane Processes, J. Mallevialle, P. E. Odendaal, and M. R. Weisner (Eds.), McGraw-Hill Publishers, New York.
Ishida, K, Milstead, C.E., Ridgway, H.F. and R. L. Riley.  1995.  Identification and evaluation of biocides for ROWPU systems.  Final project report submitted to U. S. Army, USA Tank and Automotive Command, Mobility Tech CTR, Fort Belvoir, VA.
Leddy, M.B., Phipps, D.W. and H.F. Ridgway.  1995.  Catabolite-mediated mutations in alternate toluene degradative pathways in Pseudomonas putida.  J. Bacteriol. 177, 4713-4720.
Ball, H.A., Reinhard, M., Orwin, E., Ridgway, H.F. and D.W. Phipps.  1993.  Factors influencing the anaerobic biodegradation of gasoline hydrocarbons by groundwater bacteria at Seal Beach, CA.  Final project report No. SU89-15, U. S. Dept. of the Navy, Environmental Protection Division, Code ESC411, Naval Facilities Engineering Service Center, Port Hueneme, CA.
Gersberg, R.M., Dawsey, W.J. and H.F. Ridgway.  1993.  In-situ microbial degradation of gasoline.  Final project report No. RP-2795-2, Electric Power Research Institute.
Rodriguez, G.G., Phipps, D., Ishiguro, K. and H.F. Ridgway.  1992.  Use of a fluorescent redox probe for direct visualization of actively respiring bacteria.  Appl. Environ. Microbiol. 58, 1801-1808.
Schaule, G., Flemming, H.-C. and H.F. Ridgway.  1992.  Use of 5-cyano-2,3-ditolyl tetrazolium chloride (CTC) for quantifying planktonic and sessile respiring bacteria in drinking water.  Appl. Environ. Microbiol. 59, 3850-3857.
Ridgway, H.F. and J. Safarik.  1991.  Biofouling of reverse osmosis membranes, pp. 81-111.  In H.-C. Flemming and G.G. Geesey (Eds.), Biofouling and Biocorrosion in Industrial Water Systems, Springer-Verlag, Berlin.
Ridgway, H.F., Safarik, J., Phipps, D., Carl, P. and D. Clark.  1990.  Identification and catabolic activity of well-derived gasoline-degrading bacteria from a contaminated aquifer.  Appl. Environ. Microbiol. 56, 3565-3575.
Ridgway, H.F., Phipps, D.W., Safarik, J., Haag, F., Reinhard, M., Ball, H., and P. L. McCarty.  1989.  Investigation of the transport and fate of gasoline hydrocarbon pollutants in groundwater.  Final project report submitted to the U. S. Geological Survey; contract grant No. 14-08-0001-G1126.
Ridgway, H. F.,  Microbial Adhesion and Biofouling of Reverse Osmosis Membranes, In Parekh, B. (Ed),  Reverse Osmosis Technology:  Application for High-Purity Water Production, Marcel Dekker, Inc., New York and Basel (1988).
Ridgway, H.F. and R.A. Lewin.  1988.  Characterization of gliding motility in Flexibacter polymorphus.  Cell Mot. Cytoskel. 11, 46-63.
Ridgway, H.F.  1987.  Microbial fouling of reverse osmosis membranes:  genesis and control, pp. 138-193.  In M.W. Mittleman and G.G. Geesey (Eds.), Biological Fouling of Industrial Water Systems: A Problem Solving Approach, Water Micro Associates, San Diego.
Ridgway, H.F., Rogers, D.M. and D.G. Argo.  1986.  Biofilm on reverse osmosis membranes.  Water and Waste Treatment 63, 45-48.
Ridgway, H.F., Rigby, M.G. and D.G. Argo.  1985.  Bacterial adhesion and fouling of reverse osmosis membranes.  J. Amer. Water Works Assoc. 77, 97-106.
Ridgway, H.F., Rigby, M.G. and D.G. Argo.  1984.  Adhesion of a Mycobacterium sp. to cellulose diacetate membranes used in reverse osmosis.  Appl. Environ. Microbiol. 47, 61-67.
Ridgway, H.F., Justice, C.A., Whittaker, C., Argo, D. and B.H. Olson.  1984.  Biofilm fouling of RO membranes:  its nature and effect on treatment of water for reuse.  J. Amer. Water Works Assoc. 76, 94-102.
Whittaker, C., Ridgway, H.F. and B.H. Olson.  1984.  Evaluation of cleaning strategies for removal of biofilm from reverse osmosis membranes.  Appl. Environ. Microbiol. 48, 395-403.
Ridgway, H.F., Justice, C., Kelly, A. and B.H. Olson.  1983.  Microbial fouling of reverse osmosis membranes used in advanced wastewater treatment technology:  chemical, bacteriological, and ultrastructural analyses.  Appl. Environ. Microbiol. 45, 1066-1084.
Ridgway, H.F. and R.A. Lewin.  1983.  Subunit composition of goblet-shaped particles from the cell wall of Flexibacter polymorphus.  Can. J. Microbiol. 29, 1689-1693.
Leong, L.Y.C., Otsaka, D., Ridgway, H.F. and B.H. Olson. 1981.  Chlorine resistance of coliform-tested bacteria isolated from raw and treated sewage effluents.  Prog. in Water Technol.
Ridgway, H.F., Means, E.G. and B.H. Olson.  1981.  Iron bacteria in drinking water distribution systems: elemental analysis of Gallionella stalks using x-ray energy dispersive microanalysis.  Appl. Environ. Microbiol. 41, 288-297.
Means, E.G., Hanami, L., Ridgway, H.F. and B.H. Olson.  1981.  Enumeration of bacteria in potable water distribution systems:  evaluation of media and plating techniques.  J. Amer. Water Works Assoc. 73, 585-590.
Ridgway, H.F. and B.H. Olson.  1981.  Scanning electron microscope evidence for bacterial colonization of a drinking water distribution system.  Appl. Environ. Microbiol. 41, 274-287.
Simon, M.I., Silverman, M., Matsumura, P., Ridgway, H., Komeda, Y. and M. Hilman.  1978.  Structure and function of bacterial flagella.  Symposia of the Society for General Microbiology, No. XXVIII, Relations Between Structure and Function in the Procaryotic Cell, pp. 271-286.
Ridgway, H.F.  1977.  The source of energy for gliding motility in Flexibacter polymorphus:  effects of metabolic and respiratory inhibitors on gliding movement.  J. Bacteriol. 131, 544-556.
Ridgway, H.F.  1977.  Ultrastructural characterization of goblet-shaped particles from the cell wall of Flexibacter polymorphus.  Can. J. Microbiol. 23, 1201-1213.
Ridgway, H.F., Silverman, M. and M.I. Simon.  1977.  Localization of proteins controlling motility and chemotaxis in Escherichia coli.  J. Bacteriol. 132, 657-665.
Ridgway, H.F., Wagner, R.M., Dawsey, W.T. and R.A. Lewin.  1975.   Fine structure of the cell envelope layers of Flexibacter polymorphus.   Can. J. Microbiol. 21, 1733-1750
Ridgway, H.F. and R.A. Lewin.  1973.  Goblet-shaped sub-units from the wall of a marine gliding microbe.  J. Gen. Microbiol. 79, 119-128.

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